منابع مشابه
Dmd059295 1438..1446
Cilengitide is a stable cyclic pentapeptide containing an Arg-GlyAsp motif responsible for selective binding to aVb3 and aVb5 integrins. The candidate drug showed unexpected inhibition of cytochrome P450 (P450) 3A4 at high concentrations, that is, a 15-mM concentration caused attenuation of P450 3A4 activity (depending on the probe substrate): 15–19% direct inhibition, 10–23% time-dependent inh...
متن کاملThe revolt of youth: some historical comparisons.
The existence of a youth problem appears to many a phenomenon peculiarly characteristic of our own time. In fact, in the United States over the past fifty years almost each generation has produced distinctive young rebels-the bohemians before and after World War I, the radicals of the thirties and forties, the beatniks and hipsters of the fifties, and the hippies and romantic anarcho-marxists o...
متن کاملDmd056887 1432..1437
This study was performed to identify genetic polymorphisms in multidrug and toxin extrusion 2-K (MATE2-K, SLC47A2), a proton/ organic cation antiporter that plays a role in the transport of organic cations across the apical membrane in kidney epithelial cells into the urine, and to demonstrate their effects on MATE2-K functions in vitro. Four of the thirty single nucleotide polymorphisms (SNPs)...
متن کاملDev118364 1437..1446
Protophloem is a specialized vascular tissue in growing plant organs, such as root meristems. InArabidopsismutants with impaired primary root protophloem differentiation, brevis radix (brx) and octopus (ops), meristematic activity and consequently overall root growth are strongly reduced. Second site mutation in the protophloem-specific presumed phosphoinositide 5-phosphataseCOTYLEDONVASCULAR P...
متن کاملFormation of the planet around the millisecond pulsar J1719–1438
Context. Recently the discovery of PSR J1719–1438, a 5.8 ms pulsar with a companion in a 2.2 hr orbit, was reported. The combination of this orbital period and the very low mass function is unique. The discoverers, Bailes et al., proposed an ultracompact X-ray binary (UCXB) as the progenitor system. However, the standard UCXB scenario would not produce this system as the time required to reach ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Slavic Review
سال: 1977
ISSN: 0037-6779,2325-7784
DOI: 10.2307/2494669